Control of Hoxd Genes' Collinearity during Early Limb Development
نویسندگان
چکیده
منابع مشابه
Control of Hoxd genes' collinearity during early limb development.
Hoxd genes are essential for limb growth and patterning. They are activated following a complex transcriptional regulation, leading to expression domains that are collinear in both space and time. To understand the mechanism(s) underlying collinearity, we produced and analyzed a set of mouse strains containing systematic deletions and duplications within the HoxD cluster. We show that two waves...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2006
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2005.11.014